At Vascular Surgery Associates, our leading vascular specialists in Los Angeles and Santa Monica provide expert care for Chronic Limb-Threatening Ischemia (CLTI), a severe form of peripheral artery disease (PAD) that significantly increases the risk of limb loss. With advanced diagnostic tools and cutting-edge treatments, we focus on restoring blood flow and preventing amputations for patients with severe arterial blockages.

What is Chronic Limb-Threatening Ischemia (CLTI)?

CLTI is an advanced stage of peripheral artery disease (PAD) where severely reduced blood flow to the lower limbs causes chronic pain, non-healing wounds, and gangrene. It is a critical medical condition requiring urgent intervention to save the affected limb and improve the patient’s overall health.

According to the American Heart Association, approximately 11% of patients with PAD progress to CLTI, and without proper treatment, up to 50% of CLTI patients face amputation within a year.

Symptoms of Chronic Limb-Threatening Ischemia

Patients with CLTI may experience:

  • Severe pain in the legs or feet even when at rest
  • Non-healing wounds or ulcers on the feet or toes
  • Gangrene or blackened tissue due to lack of blood supply
  • Cold, pale, or discolored skin in the affected limb
  • Weakened pulses in the feet and ankles

If left untreated, CLTI can lead to severe infections, disability, and limb amputation.

Risk Factors for CLTI

Several conditions and lifestyle factors increase the risk of developing CLTI, including:

Diabetes

A major contributor to poor circulation and non-healing wounds

Smoking

A leading cause of arterial damage and plaque buildup

High blood pressure and cholesterol

Accelerate arterial narrowing and blockages

Atherosclerosis

Hardening of the arteries that restricts blood flow

Kidney disease

Increases the risk of vascular complications

History of PAD or Vascular Disease

Increases the likelihood of arterial blockages and reduced blood flow

Advanced Diagnosis for CLTI

At Vascular Surgery Associates, we use state-of-the-art imaging and vascular testing to diagnose CLTI, including:

Ankle-Brachial Index (ABI) Test

Measures blood pressure differences in the arms and legs to assess circulation

Doppler Ultrasound

Identifies blocked arteries and reduced blood flow

CT and MR Angiography

Provides detailed images of the arteries to locate obstructions

Catheter-Based Angiography

Allows direct visualization of the arteries for treatment planning

Cutting-Edge Treatments for CLTI

Our Los Angeles and Santa Monica vascular specialists offer the most advanced treatments to restore blood flow and prevent amputations:

Angioplasty & Stenting

A minimally invasive procedure where a balloon is used to open blocked arteries, often followed by stent placement to keep the vessel open

Atherectomy

A specialized procedure that removes plaque buildup from arteries to improve blood flow

Bypass Surgery

Creates a new pathway for blood flow using a graft to bypass blocked arteries

Endovascular Therapies

Innovative catheter-based treatments to restore circulation with less pain and faster recovery

Wound Care & Limb Salvage

A multidisciplinary approach that includes wound debridement, infection control, and advanced dressings to prevent amputations

Frequently Asked Questions About CLTI

CLTI is the most severe stage of PAD, where blood flow is critically reduced, leading to chronic pain, non-healing ulcers, and gangrene.

While the damage cannot always be reversed, early intervention with angioplasty, stenting, or bypass surgery can significantly improve blood flow and prevent limb loss.

Without treatment, CLTI can result in serious infections, gangrene, and amputation. Early diagnosis and vascular intervention are critical to saving the limb.

With advanced vascular treatments, up to 80-90% of patients can avoid major amputations, according to recent studies.

Quitting smoking, controlling diabetes, eating a heart-healthy diet, and regular exercise can help improve circulation and prevent disease progression.

Logo of Vascular Surgery Associates, A Professional Corporation, featuring a stylized blood vessel design with "Est. 1963" in the center.

Dedicated to Excellence in Vascular Care Since 1963

Vascular Surgery Associates (VSA) has established itself as a cornerstone of vascular health in Southern California, combining decades of experience with cutting-edge treatment methods. Founded by visionary surgeons in 1963, our practice has grown from pioneering beginnings into one of the busiest and most respected vascular surgery groups in the Western United States.

About Us

Schedule a Consultation for CLTI Treatment in Los Angeles and Santa Monica

If you are experiencing leg pain, non-healing wounds, or signs of CLTI, don’t wait. At Vascular Surgery Associates, our expert vascular surgeons in Los Angeles and Santa Monica specialize in minimally invasive procedures and limb-saving treatments to restore blood flow and improve your quality of life.

Contact us today to schedule a consultation.

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Learn How Our Expert Care Has Changed Lives for the Better

Dr Tulloch and his very competent and experienced team performed three relatively minor procedures to improve the circulation in my lower legs. ( I am 80.) After only six weeks, improvements were very noticeable, including reduced swelling, shrinking of three small venous ulcers, improved skin condition and easier walking / hiking.
Mitja Hinderks
Dr. Moridzadeh is absolutely an amazing doctor, and human being. So very nice, approachable, and an excellent listener. Very knowledgeable in all areas, in addition to his specialty. You are in good hands with Dr. Moridzadeh. He is the top of the line. First class doctor! So happy I was referred to him!
Barbara Koval

Your Trusted Vascular & Vein Specialists in Los Angeles & Santa Monica, CA

Our expertise spans all areas of vascular surgery, from diagnosing complex conditions to performing advanced therapeutic procedures. Our physicians are not only leaders in the field but also dedicated mentors to the next generation of vascular surgeons. They actively contribute to the medical community through extensive research and publication in peer-reviewed journals.

Leaders in Minimally Invasive Vein Care Solutions

Our surgeons excel in minimally invasive techniques for treating abdominal aortic aneurysms, peripheral artery blockages, and venous diseases, ensuring quicker recoveries and less discomfort for our patients. This patient-focused approach is why individuals in need of vein and artery care choose us for their treatment.

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Santa Monica Office

2021 Santa Monica Blvd #535e
Santa Monica CA 90404

Los Angeles Office

8631 West 3rd St. #615E
Los Angeles CA 90048

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