Post-Thrombotic Syndrome (PTS) is a chronic complication that develops after deep vein thrombosis (DVT), leading to persistent leg pain, swelling, and skin changes. Up to 50% of individuals who experience a DVT will develop PTS within two years, making it a serious concern for those with a history of blood clots. This condition occurs due to damage to the vein walls and valves, which impairs circulation and causes long-term discomfort.
At Vascular Surgery Associates, our leading vascular specialists in Los Angeles and Santa Monica offer advanced diagnostic techniques and cutting-edge treatment solutions to help patients manage symptoms, restore blood flow, and improve their quality of life.
How Does Post-Thrombotic Syndrome Develop?
PTS occurs when a blood clot in a deep vein (DVT) damages the vein’s inner lining, leading to chronic inflammation, poor blood flow, and valve dysfunction. This causes persistent swelling, pain, and venous pressure, which can result in skin changes, ulcers, and a heavy sensation in the legs.
While not everyone who experiences a DVT will develop PTS, the risk increases with:
- Untreated or recurring DVTs that cause progressive vein damage
- Delays in seeking treatment for blood clots
- Clots in the upper thigh or pelvic veins, which affect larger circulatory pathways
- Obesity or prolonged immobility, leading to worsened venous pressure
- Incomplete clot resolution, causing chronic vein obstruction
Early intervention following a DVT diagnosis can help reduce the risk of PTS and long-term venous complications.
Recognizing the Symptoms – When to Seek Treatment
PTS symptoms often mimic those of chronic venous insufficiency (CVI) and can worsen over time. Common signs include:
- Persistent leg swelling that worsens throughout the day
- Aching, heaviness, or tightness in the affected leg
- Skin discoloration, thickening, or a leathery appearance
- Development of venous ulcers, particularly near the ankles
- Pain that worsens with standing or walking but improves with elevation
Without proper treatment, PTS can significantly impact daily activities and lead to serious complications, such as venous ulcers.
How is Post-Thrombotic Syndrome Diagnosed?
At Vascular Surgery Associates, we use advanced imaging techniques to assess venous function, detect lingering clot remnants, and evaluate the severity of PTS. Diagnostic tools include:
Doppler Ultrasound
To detect obstructions and measure blood flow in affected veins
Venous Duplex Scanning
To assess valve function and circulation
CT or MR Venography
To visualize blockages in deep veins
Intravascular Ultrasound (IVUS)
For a detailed, real-time view of vein structure
An accurate diagnosis helps determine the best course of treatment to restore circulation and relieve symptoms.
Advanced Treatment Options for Post-Thrombotic Syndrome
At Vascular Surgery Associates, we provide a combination of minimally invasive treatments, lifestyle modifications, and symptom management strategies to improve circulation and reduce discomfort associated with PTS.
Compression Therapy – Supporting Blood Flow & Reducing Swelling
Compression therapy is one of the most effective methods for managing PTS symptoms by improving circulation and reducing leg swelling. Treatment options include:
- Medical-grade compression stockings to promote venous return
- Multilayer compression bandaging for severe swelling
- Pneumatic compression devices for at-home lymphedema and swelling control
Minimally Invasive Procedures for Severe PTS
In cases where standard therapy is not enough, our specialists offer advanced vein treatments to improve blood flow and reduce symptoms.
Venous Stenting
To widen narrowed or blocked veins and improve circulation
Catheter-Directed Thrombolysis
For dissolving chronic clot remnants
Endovenous Ablation Therapy
To seal off damaged veins and redirect blood flow
These minimally invasive procedures provide long-term relief and prevent further progression of PTS-related complications.
Lifestyle & At-Home Management Strategies
Patients can help manage PTS symptoms and prevent worsening vascular damage through:
- Daily leg elevation to reduce swelling
- Regular exercise and movement to improve circulation
- Weight management to reduce vein pressure
- Proper skin care to prevent ulcers and infections
With consistent treatment and preventive care, most individuals with PTS see significant symptom improvement over time.
Frequently Asked Questions About Post-Thrombotic Syndrome
PTS symptoms can develop within weeks to months after a DVT, but in some cases, they take years to become noticeable.
There is no complete cure for PTS, but early treatment and lifestyle modifications can significantly reduce symptoms and prevent complications.
With proper care and treatment, venous ulcers can heal, but preventive measures are needed to avoid recurrence.
Not necessarily. However, without treatment, up to 50% of DVT patients develop some form of PTS, making early intervention crucial.
If you have persistent swelling, leg pain, or skin changes following a DVT, a vascular evaluation is recommended to prevent worsening symptoms.
Dedicated to Excellence in Vascular Care Since 1963
Vascular Surgery Associates (VSA) has established itself as a cornerstone of vascular health in Southern California, combining decades of experience with cutting-edge treatment methods. Founded by visionary surgeons in 1963, our practice has grown from pioneering beginnings into one of the busiest and most respected vascular surgery groups in the Western United States.
Expert Post-Thrombotic Syndrome Treatment in Los Angeles & Santa Monica
Living with Post-Thrombotic Syndrome can be frustrating and painful, but effective treatment options exist to improve circulation and reduce discomfort. At Vascular Surgery Associates, our specialists in Los Angeles and Santa Monica offer expert diagnosis, personalized treatment plans, and the latest minimally invasive procedures to help patients regain mobility and comfort.
Contact us today to schedule a consultation and take control of your vascular health.