Infections in wounds, particularly chronic or non-healing wounds, pose a serious risk to overall health, limb preservation, and recovery. Without proper infection control, wounds can lead to severe complications, including cellulitis, sepsis, and tissue death (gangrene). According to the Centers for Disease Control and Prevention (CDC), more than 8.2 million people in the U.S. require medical attention for chronic wounds annually, with many cases complicated by infections.
At Vascular Surgery Associates in Los Angeles & Santa Monica, our specialists are highly skilled in diagnosing and treating wound infections using targeted antibiotic therapy, debridement, and advanced wound care strategies to promote healing and prevent further complications.
Why Infection Control is Critical for Wound Healing
An infection occurs when bacteria, fungi, or other pathogens invade an open wound, disrupting the body’s natural healing process. When left untreated, infected wounds can lead to:
- Delayed healing due to inflammation and tissue breakdown
- Deeper tissue infections, spreading to bones (osteomyelitis) or bloodstream (sepsis)
- Increased risk of amputation, especially in diabetic patients with foot ulcers
- Systemic infections, which can be life-threatening if not treated promptly
Early detection and aggressive treatment are essential for preventing these complications and preserving healthy tissue.
Signs of a Wound Infection
Recognizing the signs of infection early is key to effective treatment and recovery. Seek medical attention if you experience:
- Redness and warmth spreading around the wound
- Swelling and pain that worsens instead of improving
- Pus, drainage, or foul-smelling discharge from the wound
- Increased tenderness or sensitivity
- Fever, chills, or fatigue, indicating a systemic infection
- Black or discolored skin, which may signal tissue death (gangrene)
If you have diabetes or poor circulation, the risk of infection is significantly higher, and wounds require immediate medical evaluation to prevent serious complications.
Advanced Infection Control & Wound Healing Treatments
At Vascular Surgery Associates, we use evidence-based infection management techniques to eliminate harmful bacteria and restore proper wound healing.
Targeted Antibiotic Therapy
After wound cultures and bacterial analysis, we prescribe customized antibiotic regimens to combat specific infections. These may include:
- Oral antibiotics for mild to moderate infections
- Intravenous (IV) antibiotics for severe or systemic infections
- Topical antimicrobial treatments to directly target bacteria at the wound site
Wound Debridement
Removing infected, dead, or damaged tissue promotes faster healing and prevents bacteria from spreading. We use:
- Sharp debridement (scalpel removal) for precise tissue removal
- Enzymatic debridement using topical agents to break down dead tissue
- Mechanical debridement with specialized dressings to gently remove bacteria
Negative Pressure Wound Therapy (NPWT)
This vacuum-assisted therapy removes infected fluids, promotes blood flow, and encourages new tissue growth. It is highly effective in treating chronic wounds, post-surgical infections, and diabetic foot ulcers.
Hyperbaric Oxygen Therapy (HBOT)
For severe infections, non-healing ulcers, and gangrene, HBOT enhances oxygen delivery to tissues, boosting the immune response and bacterial elimination.
Who is Most at Risk for Wound Infections?
Certain individuals are at higher risk for wound infections and should seek prompt wound care at the first sign of complications. Risk factors include:
- Diabetes due to poor circulation and weakened immune response
- Peripheral Artery Disease (PAD) reducing oxygen supply to tissues
- Compromised immune systems from chronic illness or medications
- Recent surgery or trauma, leading to open wounds
- Poor hygiene or inadequate wound care increasing bacterial exposure
Early intervention can prevent infections from worsening and reduce long-term complications.
Frequently Asked Questions About Infection Control & Antibiotic Therapy
Watch for redness, swelling, warmth, pain, pus, or a foul odor. If the wound worsens instead of improving, seek medical care immediately.
Untreated infections can spread to deeper tissues, bones, or the bloodstream, leading to severe illness, tissue damage, or amputation.
While antibiotics help fight bacteria, advanced treatments like debridement, NPWT, and proper wound dressings may be needed for complete healing.
Healing time varies depending on infection severity, circulation health, and treatment method, but early treatment leads to better outcomes.
Keeping wounds clean, changing dressings as directed, managing chronic conditions (like diabetes), and seeking early medical care can significantly reduce the risk of infection.

Dedicated to Excellence in Vascular Care Since 1963
Vascular Surgery Associates (VSA) has established itself as a cornerstone of vascular health in Southern California, combining decades of experience with cutting-edge treatment methods. Founded by visionary surgeons in 1963, our practice has grown from pioneering beginnings into one of the busiest and most respected vascular surgery groups in the Western United States.
Wound Infection Treatment & Antibiotic Therapy in Los Angeles & Santa Monica
Infections can severely impact wound healing, but with expert care and advanced treatments, complications can be prevented and managed effectively. At Vascular Surgery Associates, we provide comprehensive infection control and antibiotic therapy to help patients heal faster, avoid complications, and regain healthy tissue function.
Schedule an appointment today to receive specialized infection care from leading vascular and wound care experts in Los Angeles & Santa Monica.